Dilated cardiomyopathy: MedlinePlus Medical Encyclopedia

Cardiomyopathy is a disease in which the heart muscle becomes weakened, stretched, or has another structural problem.

Dilated cardiomyopathy is a condition in which the heart muscle becomes weakened and enlarged. As a result, the heart cannot pump enough blood to the rest of the body.

There are many types of cardiomyopathy. Dilated cardiomyopathy is the most common form, but it may be the result of different underlying conditions. Some health care providers use the term to indicate a specific condition, called idiopathic dilated cardiomyopathy. There is no known cause for this type of dilated cardiomyopathy.

Dilated cardiomyopathy
Dilated cardiomyopathy

The most common causes of dilated cardiomyopathy are:

Heart disease caused by a narrowing or blockage in the coronary arteries

Poorly controlled high blood pressure

There are many other causes of dilated cardiomyopathy, including:

Alcohol or cocaine (or other illegal drug) use (usually heavy use for a prolonged time)

Diabetes, thyroid disease, or hepatitis

Medicines that can be toxic to the heart, such as certain medicines used to treat cancer

Abnormal heart rhythms in which the heart beats very fast for a long period of time

Autoimmune diseases

Conditions that run in families

Infections that involve the heart muscle

Heart valves that are either too narrow or too leaky

During the last month of pregnancy, or

within 5 months after the baby is born

Exposure to heavy metals such as lead, arsenic, cobalt, or mercury

This condition can affect anyone at any age. However, it is most common in adult men.

Symptoms of heart failure are most common. They most often develop slowly over time. However, sometimes symptoms start very suddenly and may be severe.

Common symptoms are:

Chest pain or pressure (more likely with exercise)

Cough

Fatigue, weakness, faintness

Irregular or rapid pulse

Loss of appetite

Shortness of breath

with activity or after lying down (or being asleep) for a while

Swelling of feet

and ankles

During the exam, the provider may find:

The heart is enlarged.

Lung crackles (a sign of fluid buildup), heart murmur, or other abnormal sounds.

The liver is possibly enlarged.

Neck veins may be bulging.

A number of laboratory tests may be done to determine the cause:

Antinuclear antibody

(ANA),

erythrocyte sedimentation rate

(ESR), and other tests to diagnose autoimmune diseases

Antibody test to identify infections such as

Lyme disease

and HIV

Comprehensive metabolic panel

Iron tests of the blood

Serum

TSH

and

T4

test to identify thyroid problems

Tests for

amyloidosis

(blood, urine)

Heart enlargement or other problems with the structure and function of the heart (such as weak squeezing) may show up on these tests. They may also help diagnose the exact cause of the problem:

Echocardiogram

(ultrasound of the heart)

Electrocardiogram (ECG)

Cardiac stress tests

Chest x-ray

Coronary angiogram

to look at blood flow through the heart arteries to the heart muscle

Cardiac catheterization to measure pressures in and around the heart

CT scan of the heart

MRI of the heart

Nuclear heart scan

(scintigraphy, MUGA, RNV,

PET scan

)

Heart biopsy

, in which a small piece of heart muscle is removed, may be needed depending on the cause. However, this is rarely done.

Things you can do at home to take care of your condition include:

Know your body and watch for symptoms that your

heart failure

is getting worse.

Watch for changes in your symptoms, heart rate, pulse, blood pressure, and weight.

Limit

how much fluid you drink

and

how much salt (sodium)

you get in your diet (check with your provider about these).

Most people who have

heart failure need to take medicines

. Some medicines treat your symptoms. Others may help prevent your heart failure from becoming worse or may prevent other heart problems.

Procedures and surgeries you may need include:

A pacemaker to help treat slow heart rates or help your heartbeat stay in sync

A defibrillator that recognizes life-threatening heart rhythms and sends an electrical pulse (shock) to stop them

Heart bypass

(CABG) surgery or angioplasty to improve blood flow to the damaged or weakened heart muscle

Valve replacement or repair

For advanced cardiomyopathy:

A heart transplant may be recommended if standard treatments have not worked and heart failure symptoms are very severe.

Placement of a

ventricular assist device

or artificial heart may be considered.

Chronic heart failure becomes worse over time. Many people who have heart failure will die from the condition. Thinking about the type of

care you may want at the end of life

and discussing these issues with loved ones and your provider is important.

Heart failure is most often a chronic illness, which may get worse over time. Some people develop severe heart failure, in which medicines, other treatments, and surgery no longer help. Many people are at risk for deadly heart rhythms and may need medicines or a defibrillator.

Contact your provider if you have symptoms of cardiomyopathy.

Get emergency medical help right away if you have chest pain, palpitations or fainting.

Cardiomyopathy - dilated; Primary cardiomyopathy; Diabetic cardiomyopathy; Idiopathic cardiomyopathy; Alcoholic cardiomyopathy

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McMurray JJV, Pfeffer MA. Heart failure: Treatment and prognosis. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 46.

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Wilcox JE, Mann DL. Management of heart failure patients with reduced ejection fraction. In: Bonow RO, Mann DL, Tomaselli GF, et al, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 13th ed. Philadelphia, PA: Elsevier; 2026:chap 58.

Updated by: Thomas S. Metkus MD, PhD, Associate Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.