J Bacteriol. 1992 Oct;174(20):6678–6681. doi:
10.1128/jb.174.20.6678-6681.1992
Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione.
D J Jamieson
1Institute of Cell and Molecular Biology, University of Edinburgh, United Kingdom.Find articles by
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1Institute of Cell and Molecular Biology, University of Edinburgh, United Kingdom.
PMCID: PMC207652 PMID:
Abstract
Treatment of Saccharomyces cerevisiae cells with low concentrations of either hydrogen peroxide or menadione (a superoxide-generating agent) induces adaptive responses which protect cells from the lethal effects of subsequent challenge with higher concentrations of these oxidants. Pretreatment with menadione is protective against cell killing by hydrogen peroxide; however, pretreatment with hydrogen peroxide is unable to protect cells from subsequent challenge with menadione. This suggests that the adaptive responses to these two different oxidants may be distinct.
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Selected References
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