Smoking Cessation Options: Overview and How to Choose

How we reviewed this article: · Healthline

There are many options to help you quit smoking, each with their own pros and cons. Finding the approach that works best for you can help make the process easier.

Smoking is considered one of the hardest habits to kick. Nicotine has a high potential for addiction, both physically and psychologically.

Quitting often requires a combination of determination, support, and the use of quitting aids, such as nicotine replacement therapy or prescription medications.

While it may take a few attempts, you can successfully quit smoking and go on to lead a healthier life.

Nicotine replacement therapy (NRT) involves smoking cessation products that can help you manage nicotine cravings and

withdrawal symptoms

.

NRT comes in the following forms:

transdermal patch

gum

nasal spray

inhaler

sublingual tablets or lozenges

Some of these products, such as nicotine gum and patches, are available over the counter, while others, such as lozenges and inhalers, are prescription only.

NRT provides a lower dose of nicotine so you’re able to wean your body off of nicotine in a gradual and controlled manner, making it easier to quit smoking.

Research

shows that different types of NRT are all equally effective for improving smoking abstinence rates and are comparable to the medication

bupropion

(Wellbutrin).

In particular, combining NRT approaches (for example, using both gum and a patch) improve success rates compared with using only one form.

One 2018 review of 133 studies that included 64,640 participants found that all forms of NRT can increase the rate of quitting by

50% to 60%

.

Prescription oral medications, like varenicline and bupropion, can help manage cravings and withdrawal symptoms. They may be a good option if NRT hasn’t worked for you in the past.

The following medications are approved by the Food and Drug Administration (FDA) to help people quit smoking:

Varenicline (Chantix)

Varenicline (Chantix) was the first prescription medication developed specifically to help people quit smoking. It works by partially activating the nicotine receptors in the brain, reducing the pleasurable effects of smoking and decreasing withdrawal symptoms.

Research

suggests that varenicline is the most effective monotherapy treatment for tobacco dependence.

In 2021, the drugmaker Pfizer

recalled

Chantix due to high levels of nitrosamines, a potential cancer-causing compound, but FDA-approved generic versions of varenicline are still available.

Bupropion (Zyban, Wellbutrin)

Bupropion (Zyban, Wellbutrin) is an atypical

antidepressant

that acts as a dopamine and norepinephrine reuptake inhibitor. This medication can help ease cravings and withdrawal symptoms as well as reduce the pleasurable effects of nicotine, making it less likely you’ll return to smoking.

A 2020 review found that people who were taking bupropion were

52% to 77%

more likely to quit smoking than those who used a

placebo

.

However, some people in the reviewed studies stopped taking bupropion due to the onset of psychiatric symptoms. It’s known that both bupropion (and varenicline) carry a risk of psychological side effects, such as agitation, irritability, depression, or suicidal thoughts.

Nortriptyline (Pamelor)

While varenicline and bupropion are FDA approved for smoking cessation, nortriptyline is used “off label” to help people quit smoking. This means that nortriptyline is FDA approved for certain uses but not for smoking cessation. Still, it may be an option if other approaches, including other medications, haven’t worked.

Nortriptyline affects a number of neurotransmitter systems. It primarily blocks the reuptake of norepinephrine with a lesser effect on serotonin.

Research

suggests that combining medication with a form of counseling, such as therapy, is the most effective approach for quitting smoking.

A CBT therapist can help you identify and change any unhelpful thoughts and behaviors related to smoking as well as help you develop positive coping strategies to overcome cravings and other triggers.

If you’re looking for an alternative approach to quitting smoking, consider therapies such as acupuncture and hypnotherapy. You can try these methods alone or with conventional therapy.

Acupuncture

Acupuncture

is a traditional Chinese medicine technique that involves inserting fine needles into specific points on the body to stimulate the flow of energy, called

qi

.

Acupuncture is believed to reduce nicotine cravings and withdrawal symptoms through the release of natural pain relievers and mood-regulating chemicals, like serotonin and endorphins.

In a

2019 review

of 24 trials involving 3,984 participants, acupuncture was found to be more effective in achieving smoking abstinence than no intervention.

Review authors say this approach is more successful when it’s combined with counseling, a smoking cessation program, or

moxibustion

than when used alone. Moxibustion involves burning ground mugwort to warm certain points along your body.

Hypnotherapy

Hypnotherapy is a type of therapy that uses hypnosis, or a trance-like state, to help you address both the conscious and subconscious parts of your mind.

The conscious mind involves the feelings and thoughts that you’re aware of, while the subconscious mind holds the parts you’re unaware of.

Research

shows that hypnotherapy acts on the underlying impulses to weaken your desire to smoke and strengthens your will to quit. Hypnotherapy is widely promoted as an effective approach for aiding smoking cessation.

A

2014 study

found that hypnotherapy was more effective than NRT in helping 164 hospitalized participants quit smoking by 26 weeks after discharge.

Transcranial magnetic stimulation (TMS)

TMS

is a type of noninvasive brain stimulation therapy. It involves the use of electromagnetic pulses that stimulate nerve cells.

While this is a relatively new approach, a

2021 study

suggests TMS can be a helpful tool for smoking cessation, particularly for managing cravings.

Some people switch to e-cigarettes to help them quit smoking traditional cigarettes. However, it’s still unclear how effective this approach is.

A

2022 systematic review

suggests e-cigarettes may be more effective than NRT for smoking cessation. But review authors noted that more high quality research is needed to fully understand the effectiveness of e-cigarettes as a quit-smoking tool.

That said, e-cigarettes

are less harmful

than cigarettes, though they still pose a range of health risks. If you’re not quite ready to quit smoking, switching to an e-cigarette can be a less harmful option in the meantime.

When choosing a smoking cessation method, it’s important to consider the following factors:

Level of nicotine dependence: The severity of your nicotine dependence can affect the type of therapy that’s most effective for you. If you’re a heavy smoker, a healthcare professional may suggest a higher dose of NRT or a combination of NRT and medication.

Health conditions or medications: Some smoking cessation medications can interfere with health conditions or other types of medication. Be sure to discuss these issues with a healthcare professional before starting NRT or medication.

Be flexible: What works for one person may not work for another. Don’t hesitate to switch to a different approach if one isn’t working for you. Quitting smoking is a process. It may take several attempts to find what works best for you.

Smoking causes nearly

1 in 5 deaths

in the United States each year. Quitting smoking is one of the biggest steps you can take toward your health and well-being.

If you’ve tried quitting smoking without success, don’t despair. It’s common for it to take several tries before it works. The most important factor in quitting smoking is a strong determination to quit and a willingness to seek support and resources as needed.